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Xuebiao Yao, PhD
Georgia Cancer Coalition
Cancer Research Fund Awardee

Assistant Professor
Department of Physiology
Morehouse School of Medicine
720 Westview Drive, SW
Atlanta, Georgia 30310

Email: xyao@msm.edu
Phone: (404)-752-1894
Fax: (404)-752-1045

 

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Title of Project:
Molecular elucidation of ARF6-mediated breast cancer metastasis

Aims of Project:

  • Evaluate the role of ARFGAP-6 in breast cancer metastasis using model bioluminescence imaging of luciferase-transduced MDA-MB-231 cells in SCID mice along with gross (e.g., necrosis, angiogenesis, etc.) and molecular (i.e., expression of MMPs, etc.) examination of metastatic tumors
  • Determine whether ARFGAP-6 protein expression is high in metastatic breast cancer using tissue array from NCI

 

 

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