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Associate Professor, MCG Cancer Center and
Department of Biochemistry and Molecular Biology
Medical College of Georgia Cancer Center
1120 15th Street, CN-4123
Augusta, GA 30912-4810
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- Cornell University, Ithaca, NY • B.S., Biochemistry • 1992
- The Johns Hopkins University School of Medicine, Baltimore, MD • Ph.D., Department of Pharmacology and Molecular Sciences • 1996
- The Johns Hopkins University School of Medicine, Baltimore, MD • Fellow, 1996
- Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA • Fellow, 1997
- National Institutes of Health, NICHD, Bethesda, MD • Fellow, 1999
- National Institutes of Health, National Cancer Institute, Bethesda, MD • NCI Cancer Scholar, 2000
- University of Florida College of Medicine, Shands Cancer Center, Department of Biochemistry and Molecular Biology, Gainesville, FL • Assistant Professor, 2004
Cancer Epigenetics, particularly:
- Basic epigenetic mechanisms underlying cellular DNA methylation patterns and gene expression in cancer cells
- De novo methyltransferase function in the regulation of gene expression in cancer
- DNA methyltransferase inhibition by intercalating agents
- Interrelationships between DNA methylation, histone modifications, and chromatin structure
- Development and characterization of novel DNA methyltransferase inhibitors
- Role of epigenetic modification in stem cell pluripotency
- Use of stem cells as models for examining the role of epigenetic modifications in tissue-specific differentiation and gene expression
- Epigenetic characterization of stem cells and tumor stem cells (particularly related to brain)
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