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MCG Cancer Center
Medical College of Georgia
1120 15th Street
CN 2101A
Augusta, GA 30912
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- Medical School: Maulana Azad Medical College, Delhi, India
• 1976
- Internship and Residency: St. Michael's Medical Center, Newark, NJ
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- Fellowship: Columbia University College of Physicians and Surgeons, New York, NY
• 1983
- Deregulated epigenetic mechanisms involving histone acetylation and methylation, which governs the loss of differentiation and enhanced proliferation and survival of human cancer cells.
- The role of molecular chaperones, e.g., heat shock proteins, in preserving the active conformation of the cancer associated onco-protein kinases and transcription factors and controlling cancer cell apoptosis or autophagy.
- Preclinical testing and clinical trials of novel combinations of epigenetics and molecular chaperone-targeted agents with inhibitors of oncoprotein kinases and transcription factors in leukemia/lymphoma and cancers.
- Early clinical trials in leukemia and breast caner
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